ea0081p700 | Reproductive and Developmental Endocrinology | ECE2022
Nour El Houda Mimouni
, Paiva Isabel
, Barbotin Anne-Laure
, Ezzahra Timzoura Fatima
, Plassard Damien
, Le Gras Stephanie
, Ternier Gaetan
, Pigny Pascal
, Catteau-Jonard Sophie
, Simon Virginie
, Prevot Vincent
, Boutillier Anne-Laurence
, Giacobini Paolo
Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder affecting women in reproductive age. Women with PCOS exhibit 2-3x higher levels of circulating Anti-Müllerian Hormone (AMH) as compared to healthy women and it is unclear if the elevation of AMH is a bystander effect or is driving the condition. Moreover, PCOS has a strong heritable component, however the etiopathology of the disease and the mechanisms underlying its transmission remain t...